within defined limits krovenos-nye vessels, moderately reduces blood pressure. The much shorter, in the positive treatment of reader vasospastic angina, Raynaud's syndrome nifedipine prescribed 3 times a day. Verapamil (izoptin) slowed and weakened contraction of the heart, makes it difficult to atrio-ventricular conduction, expands small coronary vessels (increasing the volume reader of Tridal Volume blood flow), moderately expanding peripheral artery disease. Digidralazin similar in properties to hydralazine. Verapamil is not recommended to use together with ?-Adre noblokatorami, as in this case is compounded by heart failure, bradycardia, disorders of atrioventricular conduction. Bevdazol (dibazol) - myotropic antispasmodic action. Applied to reduce the neurological disorders associated with spasm of cerebral vessels after subarachnoid hemorrhage. The drug is useful to combine with substances that reduce the influence of the sympathetic innervation (? blockers, reserpine), and diuretics. In combination with reserpine, and hydrochlorothiazide is a member of the tablets "Adelfan - Ezidreks. In addition, these drugs have a weak bronchodilator, tocolytic, and antiplatelet противоатеросклеротическое action. Side effects of nifedipine: tachycardia, headache, dizziness, facial flushing, toschnota, constipation, peripheral edema, particularly edema ankles (in reader schuntov expansion, satisfy the artery but not vein, inadequate venous outflow), paresthesia, myalgia, frequent urination. In connection with the anticonvulsant and antihypertensive properties of magnesium sulfate used in eclampsia (late toxicosis pregnancy, which is accompanied by convulsions and high blood-pressure). reader Unlike dihydropyridines these drugs for systemic effect weakening of the poop, and slowed heart beat difficult atrioventricular conduction. In experiments on isolated Nifedipine heart weakens and slowed reader beat. In this regard: 1) decreases vasoconstrictor action of angiotensin II; 2) decreases the stimulating effect of angiotensin II on the sympathetic nervous system; 3) decreases the stimulating effect of angiotensin II on the synthesis and secretion of aldosterone (with a decrease in aldosterone secretion increased excretion of Na + and delayed excretion of K +). Magnesium sulfate for intramuscular or intravenous injection causes a marked hypotensive effect, which is associated with myotropic vasodilating action, as well as the depressing effect on the vasomotor center reader the transfer of excitation sympathetic ganglia. In high doses of verapamil effectively reduces blood pressure, hypotensive effect is due to reduced cardiac output and Hairy Cell Leukemia peripheral vascular reader The drug has 6-8 hours for a systematic treatment of hypertension used tablets verapamil sustained release drug (Tabletkiretard) take 1 time a day at night. Among calcium channel blockers produce dihydropyridines, phenylalkylamine and benzotiazepiny. With prolonged use of hydralazine in high doses may develop syndrome of systemic lupus erythematosus (More commonly in women and "slow atsetilatorov). Effect of nifedipine on the heart is made up of two components reader the direct and reflex. Magnesium sulfate is not recommended to use during childbirth, as the drug-running lablyaet reduction myometrium. All this contributes to high blood Every bedtime Renin secretion reduces substances that reduce hundred liruyuschee influence of sympathetic innervation in the juxtaglomerular cells producing renin. Phenylalkylamine should not be combined vat with ? blockers. In addition, inhibition of ACE eliminated inactivating effect of ACE on bradykinin - bradykinin level rises. These cells contain the ? 1 adrenergic receptors, in that one component of the mechanism hypotensive action of ? blockers is to reduce the secretion of re-Nina.
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