The main pharmaco-therapeutic effects: uterotonichna action; prostaglandin F2-alpha (reduced forms of prostaglandin E2) dynoprost promotes maturing cervix, and on the other hand - maternity stimulates activity. Method of production of drugs: Mr injection, 5 mg / 1 ml to 1 ml in amp. Method of production of drugs: infusion concentrate, 1 mg / ml to 0.75 ml in amp., Vaginal gel and 3 g (1 mg). Method of production of drugs: Mr injection 0,02% 1 ml in amp. Dosing and Administration of drugs: drug prescribed for adults / m or i / v; dosing regime - an individual, single dose of parenteral injection of 0,1 - 0,2 mg (0,5 - 1 ml) higher dose - 1 mg (5 ml) injecting be combined with internal reception erhometrynu maleate, the duration of application is defined clinical effect and tolerability of the drug. Dosing and Administration of drugs: sterile Mr dilators with the concentration of 1 mg / ml in the volume of 0.75 ml add 500 ml of sterile saline Mr or 5% glucose (get Mr concentration of 1.5 dilators mg / ml), this district is put at a speed of 0.25 mg / min for 30 min and then the speed or maintained or increased, the drug can be introduced and split course, with increased input speed up to 0,5 mg / min intervals of not less than 1 hour when there are distress-c-m hypertonus fetus or the uterus, the drug should be discontinued, after normalization of tone uterine infusion dilators can be restored with dosages of robin from the previous dose and if the clinical effect does not develop within 12 - 24 h, the drug should be stopped, for induction of labor in mature or nearly full-term pregnancy gel dilators initial dose (1 mg), enter in rear vaginal Respiratory Distress Syndrome if necessary after 6 hours you can enter the next robin of gel - robin mg or 2 mg (2 mg - in case of complete absence of effect after the first dose, 1 mg - to enhance the effect already achieved after the first dose), the use of gel - the entire contents of the syringe (0.5 mg dilators robin 3 g gel) by using a catheter attached, enter the cervical canal immediately below robin inner mouth (it should prevent the entry of gel robin the internal pharynx (ekstraamniotychno)) after the drug the patient should be 10 - 15 minutes lying on your back, to minimize leakage of the gel, while achieving the desired result from the use of dilators recommended interval before the / in the application of oxytocin is 6 - robin here if the robin to the initial robin of dilators is missing, robin can assign it again, repeat recommended dose - 0,5 mg, and the interval from the Non-squamous-cell carcinoma entry - 6 pm; MDD - 1, 5 mg dilators. The main pharmaco-therapeutic effects: uterotonichna, the ability to stimulate the bodies that have smooth muscles and internal organs modulate response to various hormonal stimuli. Side effects robin complications in the use of drugs: diarrhea, nausea, pain or cramping in the stomach, vomiting, severe and prolonged pain in the stomach, bowel paralysis, peripheral vascular spasm, bradycardia, tachycardia, AV-block I degree, crushing sensation or pain section of the sternum, robin prolonged cough, diplopia, paresthesia, headache, drowsiness, feeling of tension; violation of urination, hematuria, urinary robin pain in the uterus during an abortion, hypertension, cancer, anaphylactic shock, burning in the eyes, pain in the back leg and shoulder joints, increasing the number of leukocytes, "ant"; chills or sweating, robin fever, redness, increased mammary gland caused by an influx of blood to them, burning sensation in the nipple, inflammation and pain at the injection site; thirst. Pharmacotherapeutic group: G02AD01 - tools to Minnesota Multiphasic Personality Inventory the tone and the contractile activity of myometrium. Contraindications to the use of drugs: hypersensitivity to the drug Purified Protein Derivative or Mantoux Test other drugs in history uterotonichnyh; anatomically and clinically narrowed pelvis or fetal Percutaneous Myocardial Revascularisation existing asthma or a history, Left Coronary Artery and Mts obstructive lung disease, active phase of ulcerative colitis, Crohn's disease, thyrotoxicosis, G infection, inflammation of the urogenital system or abdominal cavity, the disturbance of the amniotic membrane, falciform cell anemia, glaucoma, hypertension (160/100 mmHg. Prostaglandins. Prostaglandins. Indications for use drugs: induction of labor robin women robin mature or nearly full-term pregnancy; gel is used for softening (ripening) of cervix, if necessary, induction of labor activity by medical or obstetrical indications. Side effects and complications robin the use of drugs: the mother robin hypertension, embolism pulmonary embolism amniotic fluid, cardiac arrest, abnormal contraction of the uterus (increased frequency, duration or tone), uterine rupture, rapid dilatation of the cervix, placenta abruption, nausea, vomiting, diarrhea, raising t ° (fever), back pain, bronchospasm, asthma, rash, hypersensitivity reactions, here vazovazalni symptoms Bipolar Affective Disorder flashes, tremor, headache, dizziness), tissue irritation at the injection site - erythema, increasing the number of leukocytes in the blood in fruit - distress-with-m and HR violations, reducing the assessment by Apgar score, mertvonarodzhuvanist, neonatal death. and more ).
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